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Synthesis 2019; 51(11): 2430-2434
DOI: 10.1055/s-0037-1612415
DOI: 10.1055/s-0037-1612415
paper
Green Access to α-Haloalkyl and α-Halobenzyl Esters, Versatile Intermediates for the One-Pot Two-Step Synthesis of O,O′-Diacyl Acetals Using Zinc-Based Ionic Liquid Catalyst
Authors
Financial support from Université Lyon 1 and CNRS are warmly acknowledged.
Further Information
Publication History
Received: 28 January 2019
Accepted after revision: 16 February 2019
Publication Date:
14 March 2019 (online)
Abstract
α-Haloalkyl and α-halobenzyl esters have been synthesized using a zinc-based ionic liquid catalyst, BMIZnCl3. These esters can then react with acids without intermediate purification to obtain mixed O,O′-diacyl acetals in a one-pot process.
Key words
α-haloalkyl esters - α-halobenzyl esters - zinc - ionic liquids - prodrugs - O,O′-diacyl acetalsSupporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0037-1612415.
- Supporting Information (PDF)
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