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Synfacts 2018; 14(04): 0431
DOI: 10.1055/s-0037-1609379
DOI: 10.1055/s-0037-1609379
Polymer-Supported Synthesis
Suzuki–Miyaura Reaction Catalyzed by Cage-Templated Palladium Nanoparticles
Qiu L.
McCaffrey R.
Jin Y.
Gong Y.
Hu Y.
Sun H.
Park W.
Zhang W.
* Yunnan University, Kunming, P. R. of China and University of Colorado at Boulder, USA
Cage-Templated Synthesis of Highly Stable Palladium Nanoparticles and their Catalytic Activities in Suzuki–Miyaura Coupling.
Chem. Sci. 2018;
9: 676-680
Cage-Templated Synthesis of Highly Stable Palladium Nanoparticles and their Catalytic Activities in Suzuki–Miyaura Coupling.
Chem. Sci. 2018;
9: 676-680
Further Information
Publication History
Publication Date:
15 March 2018 (online)

Significance
A palladium nanocatalyst (PdNP@1) prepared by a cage-templated synthesis method (eq. 1), catalyzed the Suzuki–Miyaura coupling of phenylboronic acid with iodo- or bromobenzenes under microwave irradiation to give the corresponding biaryl products in 96–99% yield (eq. 2).
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Comment
PdNP@1 was characterized by means of UV–Vis, 1H NMR (DOSY), HR-TEM, and EDS analyses. In the reaction of 4-iodotoluene with phenylboronic acid, the catalyst was reused three times without loss of its catalytic activity. The reactivity of PdNP@1 was higher than that of commercially available palladium catalysts such as Pd(PPh3)4 or Pd/C.
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