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Am J Perinatol 2018; 35(01): 084-089
DOI: 10.1055/s-0037-1606184
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Supplemental Oxygen Study: A Randomized Controlled Study on the Effect of Maternal Oxygen Supplementation during Planned Cesarean Delivery on Umbilical Cord Gases

Valeria B. Simon
1   Department of Obstetrics and Gynecology, University of California, Irvine, Orange, California
,
Alex Fong
2   Department of Obstetrics and Gynecology, Miller Children's and Women's Hospital/Long Beach Memorial Medical Center, Long Beach, California
,
Michael P. Nageotte
2   Department of Obstetrics and Gynecology, Miller Children's and Women's Hospital/Long Beach Memorial Medical Center, Long Beach, California
› Author Affiliations
Further Information

Publication History

10 January 2017

15 July 2017

Publication Date:
24 August 2017 (online)

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Abstract

Objective The aim was to determine the fetal umbilical blood gas effects of supplemental maternal oxygenation compared with room air (RA) during term planned cesarean delivery.

Methods This is a prospective randomized controlled study of singleton planned cesarean deliveries randomized to receive supplemental oxygen (O2) at 10 L per minute (L/min) via facemask or RA. Umbilical cord gases were collected. The primary outcome was umbilical arterial pH level. Secondary outcomes included umbilical cord values and maternal and neonatal outcomes. Data were expressed as median ± interquartile range (IQR).

Results Seventy subjects in total were enrolled, with 65 subjects available for analysis. The median umbilical arterial pO2 was significantly increased in the supplemental O2 group (18 [13.5–20.5] mm Hg) versus RA group (16 [12–18] mm Hg), p = 0.04). The median umbilical venous pO2 was significantly increased in the supplemental O2 group (32 [26.5–36.0] mm Hg) versus RA group (28.5 [22–34.3] mm Hg), p = 0.04). There were no significant differences with other umbilical blood gas values and composite maternal or neonatal complications.

Conclusion Subjects with term singleton gestations receiving O2 at 10 L/min during cesarean delivery compared with RA demonstrated no significant change in umbilical cord pH values. There was a significant increase in umbilical cord arterial and venous O2 levels in those receiving O2.

Keywords

cesarean delivery - supplemental O2 - umbilical arterial pH - umbilical cord gases
 

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