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Synthesis 2017; 49(24): 5364-5370
DOI: 10.1055/s-0036-1590895
DOI: 10.1055/s-0036-1590895
paper
Recycled Pd/C-Catalyzed Heck Reaction of 2-Iodoanilines under Ligand-Free Conditions
Autoren
The work was supported by the Youth Science and Technology Talent Development Project in the Education Department of Guizhou Province (Grant No.qianjiaohe KY zi [2016] number 263) and by the Innovation Team of Liupanshui Normal University (Grant No. LPSSYKJTD201601).
Weitere Informationen
Publikationsverlauf
Received: 27. Juni 2017
Accepted after revision: 07. August 2017
Publikationsdatum:
28. August 2017 (online)
Abstract
Recyclable Pd/C-catalyzed Heck reaction of 2-iodoanilines with acrylate has been developed. The reaction occurred readily in 1,4-dioxane using Pd/C (10 wt%) as catalyst under ligand-free conditions, and the cross-coupling products were obtained with medium to high yield. Gram-scale reactions and recycling of the catalyst were also demonstrated.
Supporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0036-1590895.
- Supporting Information (PDF) (opens in new window)
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For the application of Heck reaction, see:
For Heck reaction in green solvents, see:
For asymmetric Heck reactions, see:
For oxidative Heck reactions, see:
For the palladium catalysis system applied in Heck reactions, see:
For Heck reaction under heterogeneous catalysis, see: