Transition-Metal- and Halogen-Free Oxidation of Benzylic sp3 C–H Bonds to Carbonyl Groups Using Potassium Persulfate

Yixin Hu; Lihong Zhou; Wenjun Lu

doi:10.1055/s-0036-1588429

Synthesis, Inhaltsverzeichnis

Synthesis 2017; 49(17): 4007-4016
DOI: 10.1055/s-0036-1588429

paper

Transition-Metal- and Halogen-Free Oxidation of Benzylic sp³ C–H Bonds to Carbonyl Groups Using Potassium Persulfate

Yixin Hu

Department of Chemistry, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, P. R. of China eMail: luwj@sjtu.edu.cn

,

Lihong Zhou

Department of Chemistry, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, P. R. of China eMail: luwj@sjtu.edu.cn

,

Wenjun Lu *

Department of Chemistry, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, P. R. of China eMail: luwj@sjtu.edu.cn

› Institutsangaben

Abstract

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Abstract

Aryl carbonyl compounds including acetophenones, benzophenones, imides, and benzoic acids are prepared from benzyl substrates using potassium persulfate as oxidant with catalytic pyridine in acetonitrile under mild conditions. Neither transition metals nor halogens are involved in the reactions.

Key words

potassium persulfate - oxidation - transition-metal-free - halogen-free - benzylic sp³ C–H bond

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Referenzen

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