Nickel-Catalyzed Reductive Cross-Coupling of Vinyl Bromides with Unactivated­ Alkyl Halides

‡ These authors contributed equally

Abstract

The use of pyridine as the sole ligand for the reductive vinylation of unactivated secondary alkyl halides under Ni-catalyzed conditions has been developed. Both alkyl- and aryl-substituted vinyl bromides are suitable, in which alkyl-decorated α-alkenyl bromides resulted in the α-products in good results.

Key words

nickel - cross-coupling - arylation - alkyl halide - catalysis

• References


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