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Synthesis 2017; 49(08): 1874-1878
DOI: 10.1055/s-0036-1588131
DOI: 10.1055/s-0036-1588131
paper
A Convenient Method for Catalytic Aromatic Pentafluoroethylation Using Potassium (Pentafluoroethyl)trimethoxyborate
Further Information
Publication History
Received: 02 November 2016
Accepted after revision: 06 December 2016
Publication Date:
22 December 2016 (online)
Abstract
A method for the copper-catalyzed pentafluoroethylation of aryl iodides using potassium (pentafluoroethyl)trimethoxyborate has been developed. The borate was found to be a convenient pentafluoroethyl source. In parallel, it was found that the solvent, as well as ligand, makes significant impact on the catalytic perfluoroalkylations.
Supporting Information
- Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0036-1588131.
- Supporting Information
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For examples of copper-catalyzed Suzuki–Miyaura couplings, see: