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Thorac Cardiovasc Surg 2017; 65(07): 581-585
DOI: 10.1055/s-0036-1584883
Short Communication
Georg Thieme Verlag KG Stuttgart · New York

Nontuberculous Mycobacteria Infection and Prognosis after Surgery of Lung Cancer: A Retrospective Study

Keiji Yamanashi
1   Respiratory Disease Center, Tazuke Kofukai Foundation, Medical Research Institute, Kitano Hospital, Osaka, Japan
,
Satoshi Marumo
1   Respiratory Disease Center, Tazuke Kofukai Foundation, Medical Research Institute, Kitano Hospital, Osaka, Japan
,
Motonari Fukui
1   Respiratory Disease Center, Tazuke Kofukai Foundation, Medical Research Institute, Kitano Hospital, Osaka, Japan
,
Cheng-Long Huang
1   Respiratory Disease Center, Tazuke Kofukai Foundation, Medical Research Institute, Kitano Hospital, Osaka, Japan
› Author Affiliations
Further Information

Publication History

12 February 2016

23 May 2016

Publication Date:
05 July 2016 (online)

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Abstract

To investigate the association between pulmonary nontuberculous mycobacteria infection (PNTMI) and prognosis after pulmonary resection for non small cell lung cancer (NSCLC), we retrospectively analyzed 391 consecutive patients with NSCLC who underwent surgery. Subjects were grouped based on with/without PNTMI defined by two criteria (12 and 23 PNTMI subjects). Kaplan–Meier analysis showed no significant difference between the two groups regarding overall survival (p = 0.800 and p = 0.912 by two criteria). PNTMI was not identified as a significant factor associated with prognosis by either univariate or multivariate analysis (hazard ratio [HR] = 0.950 and HR = 0.948, respectively).

Keywords

chest - lung cancer treatment - thoracoscopy/VATS
 

  • References

  • 1 Griffith DE, Aksamit T, Brown-Elliott BA. , et al; ATS Mycobacterial Diseases Subcommittee; American Thoracic Society; Infectious Disease Society of America. An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases. Am J Respir Crit Care Med 2007; 175 (04) 367-416
    CrossrefPubMedGoogle Scholar
  • 2 Bodle EE, Cunningham JA, Della-Latta P, Schluger NW, Saiman L. Epidemiology of nontuberculous mycobacteria in patients without HIV infection, New York City. Emerg Infect Dis 2008; 14 (03) 390-396
    CrossrefPubMedGoogle Scholar
  • 3 Prince DS, Peterson DD, Steiner RM. , et al. Infection with Mycobacterium avium complex in patients without predisposing conditions. N Engl J Med 1989; 321 (13) 863-868
    CrossrefPubMedGoogle Scholar
  • 4 Winthrop KL, McNelley E, Kendall B. , et al. Pulmonary nontuberculous mycobacterial disease prevalence and clinical features: an emerging public health disease. Am J Respir Crit Care Med 2010; 182 (07) 977-982
    CrossrefPubMedGoogle Scholar
  • 5 Daley CL, Iseman M. Mycobacterium avium complex and lung cancer: chicken or egg? Both?. J Thorac Oncol 2012; 7 (09) 1329-1330
    CrossrefPubMedGoogle Scholar
  • 6 Lande L, Peterson DD, Gogoi R. , et al. Association between pulmonary mycobacterium avium complex infection and lung cancer. J Thorac Oncol 2012; 7 (09) 1345-1351
    CrossrefPubMedGoogle Scholar
  • 7 Tamura A, Hebisawa A, Sagara Y. , et al. Coexistence of lung cancer and active pulmonary mycobacteriosis [in Japanese]. Kekkaku 2005; 80 (05) 413-419
    PubMedGoogle Scholar
  • 8 Kotilainen H, Valtonen V, Tukiainen P, Poussa T, Eskola J, Järvinen A. Clinical findings in relation to mortality in non-tuberculous mycobacterial infections: patients with Mycobacterium avium complex have better survival than patients with other mycobacteria. Eur J Clin Microbiol Infect Dis 2015; 34 (09) 1909-1918
    CrossrefPubMedGoogle Scholar