RSS-Feed abonnieren
Bitte kopieren Sie die angezeigte URL und fügen sie dann in Ihren RSS-Reader ein.
https://www.thieme-connect.de/rss/thieme/de/10.1055-s-00000131.xml
Synfacts 2016; 12(09): 0911
DOI: 10.1055/s-0035-1562556
DOI: 10.1055/s-0035-1562556
Synthesis of Materials and Unnatural Products
Molecular Knot Inducing Allosteric Control of Catalysis
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
18. August 2016 (online)
Significance
Molecular knots are found in nature and, although synthetic knots have been synthesized, the benefits of knotted molecules remain unclear. In this report, the authors synthesize a molecular knot, perform a metal exchange, and are able to establish a catalytic cycle that can be allosterically initiated and regulated.
#
Comment
The synthesis of the molecular knot is high yielding and both removal of metals and exchange is possible without uncoiling of the structure. The authors show catalytic hydrolysis, Michael addition, and Diels–Alder reactions.
#
#