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Synfacts 2016; 12(2): 0109
DOI: 10.1055/s-0035-1561110
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Synthesis of (R)-Verapamil by Enantioselective Heck Arylation

Authors

    Contributor(s):

  • Philip Kocienski

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Publication History

Publication Date:
19 January 2016 (online)

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Key words

verapamil - enantioselective Heck arylation - quaternary stereogenic centers - carbopalladation - aryldiazonium salts - trisubstituted alkenes