N-Heterocyclic Carbene Catalyzed Monoacylation of Vicinal Diols

Abstract

The N-heterocyclic carbene (NHC)-catalyzed monoacylation of vicinal diols is described. Monoacylated compounds of 1,2-, 1,3-, and 1,4-diols are obtained in good yields and selectivity under mild reaction conditions at ambient temperature.

Key words

N-heterocyclic carbene - organocatalyst - vicinal diol - monoselectivity - acylation - monoprotection

• References

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