Am J Perinatol 2015; 32(13): 1225-1230
DOI: 10.1055/s-0035-1552940
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Accuracy of Estimated Blood Loss in Predicting Need for Transfusion after Delivery

Shayna N. Conner
1   Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri
,
Methodius G. Tuuli
1   Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri
,
Ryan Colvin
1   Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri
,
Anthony L. Shanks
1   Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri
,
George A. Macones
1   Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri
,
Alison G. Cahill
1   Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri
› Author Affiliations
Further Information

Publication History

02 October 2014

28 March 2015

Publication Date:
22 May 2015 (online)

Abstract

Objective The definition of postpartum hemorrhage (PPH) was developed more than 50 years ago. Since then, the obstetric population has changed dramatically. We sought to determine how well we estimated blood loss (EBL) and find thresholds predicting need for transfusion.

Study Design We performed a prospective cohort study from 2010 to 2012, comparing those who needed transfusion postpartum and those who did not. EBL, calculated EBL (cEBL), and change in hematocrit were calculated for patients who did not receive transfusion, and EBL was calculated for those who did receive transfusion, stratified by delivery type. Receiver operator curves were created and optimal thresholds of EBL to predict transfusion were estimated.

Results Among 4,804 patients, transfusion was required for 0.65% of vaginal and 8.7% of cesarean deliveries. Median EBL was higher in women requiring transfusion. A weak correlation was noted between EBL and cEBL for all deliveries. Thresholds of 500 mL blood loss for vaginal delivery and 1,000 mL for cesarean had the best predictive ability for transfusion.

Conclusion In this modern obstetric, cohort EBL is weakly correlated with cEBL, suggesting that accuracy of clinical estimates of blood loss is modest. However, EBL predicts need for transfusion, with optimal thresholds of 500 mL for a vaginal delivery and 1,000 mL in a cesarean. This validates the traditional definitions of PPH in our modern population.

This abstract was a poster presentation at the Annual Meeting of the Society of Maternal Fetal Medicine, February 3–8, 2014, New Orleans, Louisiana.


 
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