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Synthesis 2015; 47(09): 1309-1316
DOI: 10.1055/s-0034-1380401
DOI: 10.1055/s-0034-1380401
paper
Palladium-Catalyzed ortho-Acylation of 2-Aryl-1,2,3-triazoles with Toluene Derivatives
Further Information
Publication History
Received: 01 December 2014
Accepted after revision: 23 January 2015
Publication Date:
27 February 2015 (online)
Abstract
A palladium-catalyzed ortho-acylation of 2-aryl-1,2,3-triazoles was developed in which low-toxicity, stable, commercially available toluene derivatives were used as acyl sources. A wide variety of aryl ketones containing 1,2,3-triazoles were obtained in moderate to excellent yields. A plausible mechanism is proposed.
Supporting Information
- Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0034-1380401.
- Supporting Information
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