Tin(II) Chloride Catalyzed Synthesis of New Pyrazolo[5,4-b]quinolines under Solvent-Free Conditions

Abstract

A series of new pyrazolo[5,4-b]quinoline derivatives were synthesized in good yields by tin(II) chloride dihydrate catalyzed cyclocondensation of 5-amino-3-(arylamino)-1H-pyrazole-4-carbonitriles with cyclohexane-1,3-dione or dimedone. The synthetic procedure can be carried out by means of simple operations under convenient solvent­-free conditions.

Keywords

heterocycles - cyclizations - catalysis - tin(II) chloride - quinolines - pyrazoles

• References

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