Synthesis 2015; 47(08): 1109-1116
DOI: 10.1055/s-0034-1380131
paper
© Georg Thieme Verlag Stuttgart · New York

Synthesis of Pyrido[2,3-c]coumarin Derivatives by an Intramolecular Povarov Reaction

Md. Belal
a   Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781 039, India
,
Deb K. Das
a   Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781 039, India
,
Abu T. Khan*
a   Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781 039, India
b   Vice-Chancellor, Aliah University, IIA/27, New Town, Near Eco-Space, Kolkata-700 156, West Bengal, India   Email: atk@iitg.ernet.in
› Author Affiliations
Further Information

Publication History

Received: 07 July 2014

Accepted after revision: 05 January 2015

Publication Date:
11 February 2015 (online)


Abstract

Fused pyrido[2,3-c]coumarin derivatives were prepared by an intramolecular Povarov reaction of 2-(propagyloxy)benzaldehydes with 3-aminocoumarins in the presence of 10 mol% of triflic acid as a catalyst in refluxing acetonitrile. Among the advantages of this protocol are shorter reaction times, good yields, and the absence of the need for aqueous workup and chromatographic separation.

Supporting Information

 
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