Synlett 2015; 26(03): 404-407
DOI: 10.1055/s-0034-1379734
letter
© Georg Thieme Verlag Stuttgart · New York

Microwave-Assisted Catalyst-Free Synthesis of Substituted 1,2,4-Triazoles

Authors

  • Ganesh M. Shelke

    a   Department of Chemistry, Birla Institute of Technology and Science, Pilani, Rajasthan 333 031, India   Email: anilkumar@pilani.bits-pilani.ac.in
    b   Department of Biology and Chemistry, Nipissing University, North Bay, ON P1B 8L7, Canada
  • V. Kameswara Rao

    a   Department of Chemistry, Birla Institute of Technology and Science, Pilani, Rajasthan 333 031, India   Email: anilkumar@pilani.bits-pilani.ac.in
  • Mukund Jha

    b   Department of Biology and Chemistry, Nipissing University, North Bay, ON P1B 8L7, Canada
  • T. Stan Cameron

    c   Department of Chemistry, Dalhousie University, Halifax, NS, B3H 4R2, Canada
  • Anil Kumar*

    a   Department of Chemistry, Birla Institute of Technology and Science, Pilani, Rajasthan 333 031, India   Email: anilkumar@pilani.bits-pilani.ac.in
Further Information

Publication History

Received: 25 October 2014

Accepted after revision: 16 November 2014

Publication Date:
07 January 2015 (online)


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Abstract

A simple, efficient, and mild method has been developed for the synthesis of substituted 1,2,4-triazoles from hydrazines and formamide under microwave irradiation. The reaction proceeds smoothly in the absence of a catalyst and shows excellent functional-group tolerance.

Supporting Information