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Synthesis 2015; 47(05): 679-691
DOI: 10.1055/s-0034-1378943
paper
© Georg Thieme Verlag Stuttgart · New York

Synthesis of Enantiomerically Pure 2-Heteroaromatic-Substituted 1,2-Amino Alcohols from Chiral tert-Butanesulfinyl Aldimines

Yantao Chen*
a   AstraZeneca Innovative Medicines Cardiovascular and Metabolic Diseases, 431 83 Mölndal, Sweden   eMail: yantao.chen@astrazeneca.com
,
Frederick W. Goldberg
b   AstraZeneca Innovative Medicines Oncology, Alderley Park, Macclesfield, Cheshire, SK10 4TG, UK
,
Jian Xiong
c   WuXi AppTec (Shanghai) Co., Ltd., No. 1 Building, #288 FuTe ZhongLu, WaiGaoQiao Free Trade Zone, Shanghai 200131, P. R. of China
,
Shujun Wang
c   WuXi AppTec (Shanghai) Co., Ltd., No. 1 Building, #288 FuTe ZhongLu, WaiGaoQiao Free Trade Zone, Shanghai 200131, P. R. of China
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