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Synfacts 2014; 10(8): 0877
DOI: 10.1055/s-0034-1378469
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart · New York

Ligand-Controlled Copper-Catalyzed Oxidation of Benzylamines with Oxygen

Contributor(s):
Yasuhiro Uozumi
,
Makoto Nagaosa
Wang J, Lu S, Cao X, * Gu H. * Soochow University, Suzhou, P. R. of China
Common Metal of Copper(0) as an Efficient Catalyst for Preparation of Nitriles and Imines by Controlling Additives.

Chem. Commun. 2014;
50: 5637-5640
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Further Information

Publication History

Publication Date:
18 July 2014 (online)

 
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Key words

red copper - benzylamines - oxidation - nitriles - imines

Significance

Commercially available red copper catalyzed the oxidation of benzylamines with molecular dioxygen in the presence of isoquinoline or 1,10-phenanthroline to give the corresponding benzonitriles (eq. 1) or dibenzylimines (eq. 2).


 

Comment

The SEM analyses of the catalyst before and after the reaction showed that the surface of the catalyst was roughened during the ­reaction to suggest leaching of copper.


 

 


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