Abstract
Since the clinical introduction of magnetic resonance imaging (MRI), the chest has
been one of its most challenging applications, and since the 1980s many physicists
and radiologists have been trying to evaluate images for various lung diseases as
well as mediastinal and pleural diseases. However, thoracic MRI could not yield image
quality sufficient for a convincing diagnosis within an acceptable examination time,
so MRI did not find acceptance as a substitute for computed tomography (CT) and other
modalities. Until the 2000, thoracic MRI was generally used only for select, minor
clinical indications. Within the past decade, however, technical advances in sequencing,
scanners and coils, adaptation of parallel imaging techniques, utilization of contrast
media, and development of postprocessing tools have been developed. In addition, pulmonary
functional MRI has been extensively researched, and MR is being assessed as a new
research and diagnostic tool for pulmonary diseases. State-of-the art thoracic MRI
now has the potential as a substitute for traditional imaging techniques and/or to
play a complimentary role in patient management. In this review, we focus on these
advances in MRI for thoracic oncologic imaging, especially for pulmonary nodule assessment,
lung cancer staging, mediastinal tumor diagnosis and malignant mesothelioma evaluation,
prediction of postoperative lung function, and prediction or evaluation of therapeutic
effectiveness. We also discuss the potential and limitations of these advances for
routine clinical practice in comparison with other modalities such as CT, positron
emission tomography (PET), PET/CT, or nuclear medicine studies.
Keywords
lung - mediastinum - pleura - MRI - CT - oncology
