Endoscopy 2013; 45(S 02): E387-E388
DOI: 10.1055/s-0033-1344824
Cases and Techniques Library (CTL)
© Georg Thieme Verlag KG Stuttgart · New York

A new attachment hood (Nanoshooter) for transnasal endoscopic submucosal dissection of the hypopharynx

Masakatsu Nakamura
1  Department of Gastroenterology, Kanazawa Medical University, Daigaku, Uchinada-machi, Ishikawa, Japan
,
Hisakazu Shiroeda
1  Department of Gastroenterology, Kanazawa Medical University, Daigaku, Uchinada-machi, Ishikawa, Japan
,
Tomomitsu Tahara
2  Department of Gastroenterology, Fujita Health University, Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, Japan
,
Tomoyuki Shibata
2  Department of Gastroenterology, Fujita Health University, Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, Japan
,
Tomiyasu Arisawa
1  Department of Gastroenterology, Kanazawa Medical University, Daigaku, Uchinada-machi, Ishikawa, Japan
› Author Affiliations
Further Information

Corresponding author

Tomiyasu Arisawa
Department of Gastroenterology
Kanazawa Medical University
1-1, Daigaku
Uchinada-machi
Ishikawa 920-0293
Japan   
Fax: +81-76-2860892   

Publication History

Publication Date:
27 November 2013 (online)

 

Endoscopic submucosal dissection (ESD) in the pharyngeal region is considered difficult. When ESD is carried out transorally for a tumor in the pharynx, the patient must be sedated [1]. However, we have carried out, without sedation, ESD with a transnasal endoscope and our novel endoscopic attachment hood for this area. There is evidence that our method may be associated with reduced incidence of hemorrhage and perforation [2]. Here, we report on the use of ESD in the treatment of pharyngeal dysplasia.

We have recently developed an attachment hood (TOP-16561, Nanoshooter) with a waterjet channel as well a suction channel for removing the residual water from the hood ([Fig. 1]), which we use with a transnasal endoscope (EG-530N2, Fujifilm, Tokyo, Japan; this is the only transnasal endoscope that can be used with a high-frequency electrosurgical system). The dysplastic lesion appeared as a brownish area, and irregular vessels were evident with a narrow-band imaging optical zoom endoscope ([Fig. 2]). We used our original precutting knife for resection and ICC200 (ERBE USA, Marietta, Georgia, USA) with the conventional settings. Without use of sedation, the endoscope with the Nanoshooter attached to it was inserted transnasally and a 1 : 1 mixture of lidocaine and 0.4 % hyaluronic acid [3] was injected submucosally ([Fig. 3]). After lifting the lesion, complete resection was carried out. After resecting the mucosal layer and trimming around the lesion, we used a snare to resect the lesion, reducing the procedure time ([Fig. 4]) to approximately 30 minutes in total ([Video 1]).

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Fig. 1 The Nanoshooter: a water being discharged from a waterjet channel; and b the waterjet and suction channels.
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Fig. 2 Dysplastic lesion in the pharynx. a The dysplastic lesion (encircled). b Lesion appearing as a brownish area with narrow-band imaging optical zoom endoscopy. c Irregular vessels in the area.
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Fig. 3 Endoscopic submucosal dissection (ESD) using a transnasal endoscope with the Nanoshooter: part 1. a The endoscope with the Nanoshooter attached to it was inserted transnasally. b A mixture of lidocaine and hyaluronic acid was injected into the submucosal layer. c The mucosal layer was incised. d Finally, an incision was made around the lesion.
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Fig. 4 Endoscopic submucosal dissection (ESD) using a transnasal endoscope with the Nanoshooter: part 2. a A snare was used to start resecting the lesion. b The dysplastic lesion was completely resected. c The resected dysplastic lesion.
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Quality:
Illustration of the procedure for transnasal endoscopic submucosal dissection (ESD) with the Nanoshooter.

Pharyngeal ESD was easily carried out with our method because the pharynx could be directly observed from straight ahead. Moreover, the procedure was done without sedation and with causing little pain to the patient. This method shows potential for esophageal ESD. In the near future, it will be possible to use this treatment method with the Nanoshooter to enable transnasal ESD, without sedation, for neoplasms of the upper gastrointestinal tract in elderly and high-risk patients with cardiopulmonary disease.

Endoscopy_UCTN_Code_TTT_1AO_2AG


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Competing interests: None


Corresponding author

Tomiyasu Arisawa
Department of Gastroenterology
Kanazawa Medical University
1-1, Daigaku
Uchinada-machi
Ishikawa 920-0293
Japan   
Fax: +81-76-2860892   


Zoom Image
Fig. 1 The Nanoshooter: a water being discharged from a waterjet channel; and b the waterjet and suction channels.
Zoom Image
Zoom Image
Fig. 2 Dysplastic lesion in the pharynx. a The dysplastic lesion (encircled). b Lesion appearing as a brownish area with narrow-band imaging optical zoom endoscopy. c Irregular vessels in the area.
Zoom Image
Zoom Image
Zoom Image
Fig. 3 Endoscopic submucosal dissection (ESD) using a transnasal endoscope with the Nanoshooter: part 1. a The endoscope with the Nanoshooter attached to it was inserted transnasally. b A mixture of lidocaine and hyaluronic acid was injected into the submucosal layer. c The mucosal layer was incised. d Finally, an incision was made around the lesion.
Zoom Image
Zoom Image
Zoom Image
Zoom Image
Fig. 4 Endoscopic submucosal dissection (ESD) using a transnasal endoscope with the Nanoshooter: part 2. a A snare was used to start resecting the lesion. b The dysplastic lesion was completely resected. c The resected dysplastic lesion.
Zoom Image
Zoom Image