Synthesis of Sultams by Ring-Closing Metathesis

Abstract

Synthesis of a series of five-membered sultams containing different hetero- or carbocycles were obtained in good to excellent yields by ring-closing metathesis (RCM) reaction. Many sultams were precipitated from the reaction mixture and they were easily separated by filtration without further purification.

Keywords

sulfonamides - sultams - sulfonylation - ring-closing metathesis - Grubbs II catalyst

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