Synlett 2014; 25(07): 951-954
DOI: 10.1055/s-0033-1340182
letter
© Georg Thieme Verlag Stuttgart · New York

Studies toward the Total Synthesis of Sorangicins: A Shortened Synthesis of the Dioxabicyclo[3.2.1]octane Core

Lars Michaelis
Chemisches Institut, Otto-von-Guericke-Universität Magdeburg, Universitätsplatz 2, 39106 Magdeburg, Germany   Fax: +49(391)6712223   Email: dieter.schinzer@ovgu.de
,
Dieter Schinzer*
Chemisches Institut, Otto-von-Guericke-Universität Magdeburg, Universitätsplatz 2, 39106 Magdeburg, Germany   Fax: +49(391)6712223   Email: dieter.schinzer@ovgu.de
› Author Affiliations
Further Information

Publication History

Received: 10 January 2014

Accepted after revision: 13 February 2014

Publication Date:
14 March 2014 (online)


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Abstract

An access to the dioxabicyclo[3.2.1]octane core of sorangicin A was developed, using a keto lactone formation, a Mukaiyama–Michael reaction and an epoxide opening as the key steps.