Novel Role of p-Toluenesulfonamide in the Preparation of 4,5-Diaminocyclopent-2-enones

Abstract

A new and efficient protocol for the preparation of 4,5-diaminocyclopent-2-enones via the reaction of N-sulfonylimine with secondary amines, with p-toluenesulfonamide acting as a leaving group, is presented. In addition, p-toluenesulfonamide worked well as a catalyst even with a catalytic amount for the reaction of 2-furaldehyde and secondary amines to afford the corresponding products in higher yields.

Key words

TsNH₂ - p-toluenesulfonamide - leaving group - catalyst - secondary amines - 4,5-diaminocyclopent-2-enones

• References

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