Selective Construction of Aliphatic Polycycles Utilizing Platinum-Catalyzed Cyclization of 2-(Enynyl)cycloalkenals

Abstract

An efficient method for the selective construction of aliphatic polycycles through platinum-catalyzed cyclization of 2-(enynyl)cycloalkenals has been developed by considering electronic (ligand) and structural (olefinic tether) effect. The presence or absence of ligand and the length of olefinic tether determine the course of the reaction after the formation of platinum–carbene complex, so that four types of aliphatic polycycles can be formed selectively.

Key words

cyclization - homogeneous catalysis - platinum - ­carbenes - carbocycles

• References

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