Abstract
Recently synthesized copper nanoparticles (Cu NP) were used to catalyze coupling of
aryl halides with diethyl malonates to produce α-aryl malonates. Synthetic conditions,
including solvents, relative amounts of reactants, catalyst, and temperature, etc.
have been varied to obtain optimum conditions for such reactions using Cu NP. Unlike
well-known cases, the present protocol developed here, with Cu NP, leads to synthesis
of a wide variety of products under not very extreme conditions.
Key words
copper nanoparticles - aryl halides - diethyl malonate - α-aryl malonates - Ullmann
coupling
