Conjunctival Extrascleral Extension of a Myeloid Sarcoma: a Clinicopathological Case Report

Introduction

Myeloid sarcoma (granulocytic sarcoma) is an extramedullary tissue infiltration by blastic cells in acute myelogenous leukaemia (AML) or myeloproliferative/myelodysplastic syndromes in blastic transformation. As the neoplastic cells contain myeloperoxidase conferring a greenish appearance to the tissue, these tumours used to be called “chloroma” [1]. In ophthalmology, they tend to develop in childrenʼs’ orbits, arising from the adjacent orbital bones. Conjunctival infiltration has only been published in less than 20 cases [2], [3], [4], [5], [6], [7], [8].

We report a myeloid sarcoma in a patient with secondary AML initially diagnosed as a scleritis, where ultrasound biomicroscopy (UBM) demonstrating a solid subconjunctival infiltration extending from the ciliary body, prompted for a conjunctivo-scleral biopsy to establish the diagnosis and treatment.

• References

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