Präexpositions-Prophylaxe zum Schutz vor HIV-Infektion – aktuelle Datenlage und Empfehlungen

Schlüsselwörter

HIV - PrEP - Prävention

Keywords

HIV - PrEP - Prevention

• Literatur

• 1 Abdool Karim Q et al. Effectiveness and safety of Tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. Science 2010; 329: 1168-74
• 2 Baeten JM et al. Antiretroviral prophylaxis for HIV prevention in heterosexual men and women. N Engl J Med 2012; 367: 399-410
• 3 Cohen MS et al. HIV treatment as prevention and HPTN 052. Curr Opin HIV AIDS 2012; 7: 106-10
• 4 Dobard C et al. Durable Protection from vaginal simian-human immunodeficiency virus infection in macaques by Tenofovir gel and its relationship to drug levels in tissue. J Virol 2012; 86: 718-25
• 5 Garcia-Lerma JG et al. Intermittent prophylaxis with oral Truvada protects macaques from rectal SHIV Infection. Sci Transl Med 2010; 2: 14ra4
• 6 Grant RM et al. Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. N Engl J Med 2010; 363: 2587-99
• 7 Juusola JL et al. The cost-effectiveness of Preexposure Prophylaxis for HIV Prevention in the United States in Men who have sex with Men. Ann Intern Med 2012; 156: 541-50
• 8 Okwundu CI et al. Antiretroviral pre-exposure prophylaxis for preventing HIV in high-risk individuals. Cochrane Database Systemic Review 2012; 11 CD007189
• 9 Salim S, Gray GE et al. Clinical decisions: Preexposure prophylaxis for HIV prevention. New Engl J Med 2012; 367: 462-5
• 10 Smith DK et al. Interim Guidance: Preexposure prophylaxis for the prevention of HIV infection in men who have sex with men. MMWR 2011; 60: 65-68
• 11 Smith DK et al. Optimal uses of Antiretrovirals for Prevention in HIV-1 serodiscordant heterosexual Couples in South Africa: a modelling Study. PloS Med 2011; 8: e1001123
• 12 Thigpen MC et al. Antiretroviral preexposure prophylaxis for heterosexual HIV transmission in Botswana. N Engl J Med 2012; 367: 423-34
• 13 Van Damme L et al. Preexposure prophylaxis for HIV infection among African women. N Engl J Med 2012; 367: 411-22
• 14 Van Sighem AI et al. Life expectancy of recently diagnosed asymptomatic HIV-infected patients approaches that of uninfected Individuals. AIDS 2010; 24: 1527-35