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Semin Respir Crit Care Med 2012; 33(05): 555-571
DOI: 10.1055/s-0032-1325164
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Update on Eosinophilic Lung Diseases

Nitin Y. Bhatt
1   Division of Pulmonary, Allergy, Critical Care Medicine, and Sleep Medicine,The Ohio State University, Columbus, Ohio
,
James N. Allen
1   Division of Pulmonary, Allergy, Critical Care Medicine, and Sleep Medicine,The Ohio State University, Columbus, Ohio
2   Department of Internal Medicine, University Hospital East, The Ohio State University, Columbus, Ohio
› Author Affiliations
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Publication History

Publication Date:
21 September 2012 (online)

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Abstract

The eosinophilic lung diseases are a group of pulmonary disorders characterized by an increase in blood and/or lung eosinophils. These disorders can be primary pulmonary disorders or the secondary manifestation of other systemic or pulmonary conditions, infection, drug reaction, or malignancy. The approach to a patient with eosinophilic lung disease involves a thorough history and physical examination, review of exposures and appropriate testing, often including bronchoscopy or lung biopsy, to establish a specific etiology and determine therapy. Eosinophilic lung disease can be suspected based on either the finding of pulmonary disease with blood eosinophilia, pulmonary disease with bronchoalveolar lavage eosinophilia, or pulmonary disease with lung tissue eosinophilia on lung biopsy.

Keywords

eosinophil - eosinophilic pneumonia - Churg-Strauss syndrome - hypereosinophilic syndrome - allergic bronchopulmonary aspergillosis - bronchocentric granulomatosis