Z-Selective Dimerization of Aromatic Terminal Alkynes Catalyzed by an 
Iridium(I)–N-Heterocyclic Carbene–Phosphine System

Calum D. Forsyth; William J. Kerr; Laura C. Paterson

doi:10.1055/s-0032-1318271

Synlett, Inhaltsverzeichnis

Synlett 2013; 24(5): 587-590
DOI: 10.1055/s-0032-1318271

letter

Z-Selective Dimerization of Aromatic Terminal Alkynes Catalyzed by an Iridium(I)–N-Heterocyclic Carbene–Phosphine System

Calum D. Forsyth

Department of Pure and Applied Chemistry, WestCHEM, University of Strathclyde, 295 Cathedral Street, Glasgow, G1 1XL, Scotland, UK Fax: +44(141)5484246 eMail: w.kerr@strath.ac.uk

,

William J. Kerr*

Department of Pure and Applied Chemistry, WestCHEM, University of Strathclyde, 295 Cathedral Street, Glasgow, G1 1XL, Scotland, UK Fax: +44(141)5484246 eMail: w.kerr@strath.ac.uk

,

Laura C. Paterson

Department of Pure and Applied Chemistry, WestCHEM, University of Strathclyde, 295 Cathedral Street, Glasgow, G1 1XL, Scotland, UK Fax: +44(141)5484246 eMail: w.kerr@strath.ac.uk

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Abstract

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Abstract

The development of an iridium-catalyzed regio- and stereoselective dimerization process has enabled the formation of (Z)-enyne products. More specifically, low catalyst loadings of an iridium(I) complex, featuring a bulky N-heterocyclic carbene–phosphine ligand combination, has been successfully employed in this selective head-to-head dimerization of terminal alkynes via C–H activation.

Key words

alkynes - enynes - dimerization - C–H activation - iridium

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Referenzen

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