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Synthesis 2012; 44(15): 2441-2447
DOI: 10.1055/s-0032-1316560
DOI: 10.1055/s-0032-1316560
paper
A Convenient Conversion of Substituted Cyclohexenones into Aryl Methyl Ketones
Further Information
Publication History
Received: 19 April 2012
Accepted after revision: 22 May 2012
Publication Date:
29 June 2012 (online)
Abstract
This work describes a straightforward multistep conversion of substrates containing a cyclohexenone moiety into mono-, bi- and tricyclic aryl methyl ketones in one single working process. Crucial steps are the addition of 1-ethoxyvinyllithium to the carbonyl group, followed by acid-catalyzed enol ether hydrolysis, dehydration, and dehydrogenation.
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