Gold-Catalyzed Skeletal Rearrangement of 1-[2-(1H-Isochromen-3-yl)aryl]ethanones with Alcohols

Abstract

A novel gold-catalyzed skeletal rearrangement of 1-[2-(1H-isochromen-3-yl)aryl]ethanones with alcohols to construct a five-membered carbocycle ring onto aromatic systems has been developed. This method serves as the first example of synthesizing inden-1-ones by a gold-catalyzed skeletal rearrangement strategy.

Key words

gold - skeletal rearrangement - 1-[2-(1H-isochromen-3-yl)aryl]ethanones - alcohols - inden-1-ones

• References


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• 10 The X-ray single-crystal diffraction analysis of 16 is given in the Supporting Information