Synthesis of the Antifungal
Cyclic Peptides Tunicyclins C and D

Harveen Kaur; Amanda M. Heapy; Margaret A. Brimble

doi:10.1055/s-0031-1290071

LETTER

Synthesis of the Antifungal Cyclic Peptides Tunicyclins C and D

Harveen Kaur^a,b, Amanda M. Heapy^a,b, Margaret A. Brimble*^a,b
^a School of Chemical Sciences, The University of Auckland, 23 Symonds Street, Auckland 1142, New Zealand
^b Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand
Fax: +64(9)3737422; e-Mail: m.brimble@auckland.ac.nz;

Abstract

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Abstract

The first synthesis of the cyclic peptides tunicyclins C and D is described. Tunicyclin D is a potent antifungal agent, isolated from a traditional Chinese medicinal herb.

Key words

cyclic peptides - tunicyclin - natural products - macrolactamisation - total synthesis

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Referenzen

References

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