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Synthesis 2012(7): 1043-1050  
DOI: 10.1055/s-0031-1289748
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

Manganese(III) Acetate Mediated Free-Radical Phosphonylation of Flavones and Coumarins

Peng Zhoua, Yao-Jia Jianga, Jian-Ping Zou*a, Wei Zhang*b
a Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry and Chemical Engineering, Suzhou University, 199 Renai Street, Suzhou, Jiangsu 215123, P. R. of China
Fax: +86(512)65880335; e-Mail: jpzou@suda.edu.cn;
b Department of Chemistry, University of Massachusetts Boston, 100 Morrissey Boulevard, Boston, MA 02125, USA
Fax: +1(617)2876030; e-Mail: wei2.zhang@umb.edu;
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Publication History

Received 29 December 2011
Publication Date:
14 March 2012 (online)

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Abstract

The phosphonyl radical generated from the reaction of manganese(III) acetate with diethyl phosphonate selectively adds to the 3-position of flavones and coumarins to afford phosphonylated products in moderate to good yields.

Key words

manganese acetate - phosphonylation - flavones - coumarins - dialkyl phosphonate - free radical

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