One-Pot Synthesis of 2,4-Dienols from Cycloalkenones

J. Ramharter; J. Mulzer

doi:10.1055/s-0031-1289358

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Synfacts 2011(12): 1350-1350
DOI: 10.1055/s-0031-1289358

Metal-Mediated Synthesis

One-Pot Synthesis of 2,4-Dienols from Cycloalkenones

Contributor(s): Paul Knochel, Nadja M. Barl
J. Ramharter, J. Mulzer*
University of Vienna, Austria

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Publication History

Publication Date:
18 November 2011 (online)

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Significance

The authors disclose a simple, efficient, and stereoselective one-pot synthesis of various 2,4-dienols by reaction of cycloalkenones with vinylmagnesium bromide or vinyllithium and subsequent treatment with acid.