Convenient Laboratory Method for
the Synthesis of Symmetrical 1,3-Diphenylacetone Derivatives

Duane R. Romer

doi:10.1055/s-0030-1260160

Synthesis, Table of Contents

PSP

Convenient Laboratory Method for the Synthesis of Symmetrical 1,3-Diphenylacetone Derivatives

Duane R. Romer
The Dow Chemical Company, Core R&D, 1776 Building, Midland, MI 48674, USA
e-Mail: drromer2@dow.com;

Abstract

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Abstract

A practical one-pot, two-step procedure for the synthesis of symmetrical 1,3-diphenylacetone derivatives from the corresponding phenylacetate has been developed. This procedure has been demonstrated by the synthesis of 1,3-diphenylacetone at the >50-gram scale in >99% purity.

Key words

condensation - ketones - esters - addition - aldol reaction

Full Text

References

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