The First Multicomponent Synthesis of Propargyl-1,2,3-triazoles [¹]

Abstract

The three-component reaction of benzotriazoles, aldehydes, and alkynes has been carried out for the first time using zinc bromide as a catalyst. The corresponding propargylbenzotriazoles are formed in high yields (79-97%) within 6-10 hours.

propargyl-1,2,3-triazole - benzotriazole - aldehyde - alkyne - zinc bromide

References

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Part 209 in the series ‘Studies on Novel Synthetic Methodologies.’

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