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Synfacts 2011(2): 0224-0224  
DOI: 10.1055/s-0030-1259372
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Flow Hydroalkylation of Styrenes under Microwave Irradiation

Contributor(s): Yasuhiro Uozumi, Yoichi M. A. Yamada, Shaheen M. Sarkar
M. Rueping*, T. Bootwicha, E. Sugiono
RWTH Aachen University, Germany
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Publication History

Publication Date:
19 January 2011 (online)

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Significance

The hydroarylation and hydroalkylation of styrenes with various arenes by using a continuous-flow microwave reactor (CF-MW) was described. A solution of the substrates was sequentially introduced into the flow cell at 1 mL/min of the flow rate to give the corresponding 1,1-di­arylethanes in up to 97% yield.