Synthesis of Chiral Cyclohexenones Using a Multicomponent
Reaction

J. Barluenga; M. G. Suero; R. De la Campa; J. Flórez

doi:10.1055/s-0030-1259345

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Synfacts 2011(2): 0179-0179
DOI: 10.1055/s-0030-1259345

Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions

Synthesis of Chiral Cyclohexenones Using a Multicomponent Reaction

Contributor(s): Mark Lautens, Stephen G. Newman
J. Barluenga*, M. G. Suero, R. De la Campa, J. Flórez
Universidad de Oviedo, Spain

Further Information

Publication History

Publication Date:
19 January 2011 (online)

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Significance

By utilizing three readily available components, chiral cyclohexenones are prepared in a single pot. Both enantiomers can be obtained in excellent selectivity by using N-acetyl-2-oxazolidinones as chiral auxiliaries.