Enantioselective Synthesis of C ₂ and C ₁ Dienes

Significance

Chiral dienes represent an important class of ligands for several asymmetric transition-metal-catalyzed transformations. Due to this fact the development of efficient and reliable protocols for the preparation of these ligands is an essential objective. In this communication, the ­authors present an enantioselective synthesis of C ₂ and C ₁ dienes based on their initial work in the field of stepwise C-H functionalization of alkenes using cobalt dinitrosoalkane complexes (J. Am. Chem. Soc. 2008, 130, 3777). The accessible products 5 can be considered as potentially interesting precursors of new chiral diene ligands.