Download PDF
Synfacts 2010(11): 1214-1214  
DOI: 10.1055/s-0030-1258714
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of Kapakahine E

Contributor(s): Steven V. Ley, Catherine F. Carter
V. R. Espejo, J. D. Rainier*
University of Utah, Salt Lake City, USA
Further Information

Publication History

Publication Date:
21 October 2010 (online)

    Permissions and Reprints

Significance

The kapakahine family of natural products was isolated from the marine sponge Cribrochalina olemda. Kapakahine E was shown to be active against P388 murine leukemia cells (IC50 = 5.0 µg/mL).