Abstract
A reliable and scalable route to racemic and highly enantiomerically
enriched menthylamines exploits the technical product rac -neomenthol as the starting material.
The elaborated protocol is based on nucleophilic substitution of
the hydroxy moiety by azide. Subsequent reduction and resolution
with tartaric acid provides the desired optically enriched menthylamines.
Key words
amines - azides - chiral resolution - reduction - terpenoids
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