Hydrophosphonylation of Benzoylhydrazones Using Iodine as a Catalyst: A Facile Synthesis of α-(N′-Acylhydrazino)-Substituted Phosphonates [¹]

Abstract

A simple and efficient method for the synthesis of α-(N′-acylhydrazino)-substituted phosphonates has been developed using the hydrophosphonylation of benzoylhydrazones with triethyl phosphite in the presence of iodine as a catalyst at room temperature. The products are formed in excellent yields (89-95%) within two to three hours.

Key words

hydrophosphonylation - benzoylhydrazones - triethyl phosphite - α-(N′-acylhydrazino)-substituted phosphonates - iodine

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Part 205 in the series ‘Studies on Novel Synthetic Methodologies’.

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1

Part 205 in the series ‘Studies on Novel Synthetic Methodologies’.