ABSTRACT
Recent studies have begun to describe the long-term outcomes of acute respiratory
distress syndrome (ARDS) survivors. These patients experience several physical, mental,
and psychological morbidities that significantly impair their health-related quality
of life (HRQL). Persistent for years after hospital discharge, decrements in functional
and neuropsychological outcomes result in lost savings, employment reduction, and
a reduction in HRQL among survivors and their caregivers. Future research should focus
on the early identification of patients and their family members at risk for long-term
sequelae, the mechanisms of injury leading to long-term ARDS consequences, and therapeutic
modalities designed to prevent or decrease these morbidities. Clinicians, caregivers,
and patients should be made aware of the deleterious long-term effects of the intensive
care unit stay because they are currently poorly recognized and potentially modifiable.
KEYWORDS
ARDS - long-term morbidity - quality of life - outcomes - cognitive and neuropsychological
outcomes
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M. Elizabeth WilcoxM.D.
Division of Pulmonary and Critical Care Medicine, Toronto Western Hospital
McLaughlin Wing 2-411P, 399 Bathurst St., Toronto, Ontario M5T 2S8, Canada
eMail: elizabeth.wilcox@uhn.on.ca