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Dtsch Med Wochenschr 2009; 134(48): 2465-2468
DOI: 10.1055/s-0029-1243030
DOI: 10.1055/s-0029-1243030
Kommentar | Commentary
Medizinisches Publizieren© Georg Thieme Verlag KG Stuttgart · New York
Weder heiliger Gral noch Teufelswerk: eine methodenkritische Bewertung der Meta-Analyse
Neither holy grail nor devil’s work: a critical appraisal of meta-analysisFurther Information
Publication History
eingereicht: 31.3.2009
akzeptiert: 13.8.2009
Publication Date:
18 November 2009 (online)

Schlüsselwörter
Kommentar - Meta-Analyse - evidenzbasierte Medizin
Keywords
comment - meta-analysis - evidence-based medicine
Literatur
- 1
AWMF, ÄZQ .
Das Leitlinien-Manual von AWMF und ÄZQ: Entwicklung
und Implementierung von Leitlinien in der Medizin.
Z Ärztl
Fortbild Qualitätsich.
2001;
95
Suppl 1
1-84
MissingFormLabel
- 2
Bailar J CI.
The promise and problems of meta-analysis.
N Engl
J Med.
1997;
337
559-561
MissingFormLabel
- 3 Best J. Damned lies and statistics: untangling numbers from the media,
politicians, and activists. The University of California Press 2001: 160
MissingFormLabel
- 4 Bortz J.
Stichprobe und Grundgesamtheit. In: Bortz J, Hrsg Statistik für Human- und Sozialwissenschaftler. 6. Aufl. Heidelberg; Springer Medizin Verlag 2009: 85-106MissingFormLabel - 5
De Angelis C D, Drazen J M, Frizelle F A. et al .
Is this clinical trial fully
registered? – A statement from the International Committee
of Medical Journal Editors.
N Engl J Med.
2005;
352
2436-2438
MissingFormLabel
- 6
Egger M, Schneider M, Smith G D.
Spurious precision? Meta-analysis of observational studies.
BMJ.
1998;
316
140-144
MissingFormLabel
- 7
Egger M, Smith G D, Schneider M, Minder C.
Bias in meta-analysis
detected by a simple, graphical test.
BMJ.
1997;
315
629-634
MissingFormLabel
- 8
Egger M, Zellweger-Zähner T, Schneider M, Junker C, Lengeler C, Antes G.
Language
bias in randomised controlled trials publsihed in English and German.
Lancet.
1997;
350
326-329
MissingFormLabel
- 9
Engels E A, Schmid C H, Terrin N, Olkin I, Lau J.
Heterogeneity and statistical significance in meta-analysis:
an empirical study of 125 meta-analyses.
Stat Med.
2000;
19
1707-1728
MissingFormLabel
- 10
Hense H -W.
Evidence-biased Medicine – oder: Die trügerische
Sicherheit der Evidenz (Zuschrift Nr. 2).
Dtsch Med Wochenschr.
2001;
126
286-288
MissingFormLabel
- 11
Hopewell S, Clarke M J, Stewart L, Tierney J.
Time to publication
of clinical trials.
Cochrane Database of Syst Rev.
2007;
2
, MR000006
MissingFormLabel
- 12
Hopewell S, Loudon K, Clarke M J, Oxman A D, Dickersin K.
Publication bias in clinical trials due to statistical significance
or direction of trial results.
Cochrane Database of Syst
Rev.
2009;
1
, MR000011
MissingFormLabel
- 13
Ioannidis J P.
Interpretation of tests of heterogeneity and bias in meta-analysis.
J Eval Clin Pract.
2008;
14
951-957
MissingFormLabel
- 14
Lau J, Ioannidis J P, Schmid C H.
Quantitative synthesis in systematic reviews.
Ann Intern Med.
1997;
127
820-826
MissingFormLabel
- 15
Lau J, Ioannidis J P, Schmid C H.
Summing up evidence: one answer is not always enough.
Lancet.
1998;
351
123-127
MissingFormLabel
- 16
Lau J, Ioannidis J P, Terrin N, Schmid C H, Olkin I.
The case of the misleading funnel plot.
BMJ.
2006;
333
597-600
MissingFormLabel
- 17
Lewis S, Clarke M.
Forest plots: trying to see
the wood and the trees.
BMJ.
2001;
322
1479-1480
MissingFormLabel
- 18
Masoudi F A, Havranek E P, Wolfe P. et al .
Most hospitalized older persons do not meet
the enrollment criteria for clinical trials in heart failure.
Am Heart J.
2003;
146
250-257
MissingFormLabel
- 19
Moher D, Cook D J, Olkin I, Rennie D, Stroup D F.
Improving the quality of reports of meta-analyses of randomised
controlled trials: the QUORUM statement.
Lancet.
1999;
354
1896-1900
MissingFormLabel
- 20
Raspe H.
„Die Heilkunde wird eine Wissenschaft sein, oder sie
wird nicht sein”. Anmerkungen zur evidenzbasierten Medizin
und ihrer Kritik durch Rogler und Schölmerich (2000).
Z Ärztl Fortbild Qualitätsich.
2001;
95
495-501
MissingFormLabel
- 21
Rogler G, Schölmerich J.
„Evidence-Biased Medicine” – oder:
Die trügerische Sicherheit der Evidenz.
Dtsch
Med Wochenschr.
2000;
125
1122-1128
MissingFormLabel
- 22
Rosenthal R.
The „file drawer problem” and tolerance for
null results.
Psychol Bull.
1979;
86
638-641
MissingFormLabel
- 23
Schulz K F, Grimes D A.
Case-control
studies: research in reverse.
Lancet.
2002;
359
431-434
MissingFormLabel
- 24
Smith G D, Phillips A N.
Smoking as „independent” risk
factor for suicide: illustration of an artifact from observational
studies?.
Lancet.
1992;
340
709-712
MissingFormLabel
- 25
Streiner D L.
I have the answer, now what’s the question? Why metaanalyses
do not provide definitive solutions.
Can J Psychiatry.
2005;
50
829-831
MissingFormLabel
- 26
Stroup D F, Berlin J A, Morton S C. et al .
Meta-analysis of observational
studies in epidemiology.
JAMA.
2000;
283
2008-2012
MissingFormLabel
- 27
Terrin N, Schmid C H, Lau J.
In an empirical evaluation of the funnel plot, researchers could
not visually identify publication bias.
J Clin Epidemiol.
2005;
58
894-901
MissingFormLabel
- 28
Thompson S G, Higgins J PT.
How should meta-regression
analyses be undertaken and interpreted?.
Stat Med.
2002;
21
1559-1573
MissingFormLabel
- 29
Thompson S G, Higgins J PT.
Can meta-analysis
help target interventions at individuals most likely to benefit.
Lancet.
2005;
365
341-346
MissingFormLabel
- 30
Zarin D A, Tse T, Ide N C.
Trial registration at ClinicalTrials.gov between May and October
2005.
N Engl J Med.
2005;
353
2779-2787
MissingFormLabel
Dr. rer. nat. Janka Koschack
Abteilung Allgemeinmedizin, Universität
Göttingen
Humboldtallee 38
37073 Göttingen
Phone: 0551/39-14225
Fax: 0551/39-14222
Email: jkoscha@gwdg.de