DMW - Deutsche Medizinische Wochenschrift, Inhaltsverzeichnis Dtsch Med Wochenschr 2009; 134(44): 2236-2238DOI: 10.1055/s-0029-1241933 Prinzip & Perspektive | Review articleVirologie, Onkologie© Georg Thieme Verlag KG Stuttgart · New YorkOnkolytische Virotherapie mit Vesikulären StomatitisvirenOncolytic virus therapy using vesicular stomatitis virusO. Ebert1 1II. Medizinische Klinik und Poliklinik, Klinikum rechts der Isar, Technische Universität München Artikel empfehlen Abstract Artikel einzeln kaufen Schlüsselwörter Onkolytische Virotherapie - Vesikuläres Stomatitisvirus - Hepatozelluläres Karzinom Keywords oncolytic virotherapy - vesicular stomatitis virus - hepatocellular carcinoma Volltext Referenzen Literatur 1 Altomonte J, Braren R, Schulz S, Marozin S, Rummeny E J, Schmid R M, Ebert O. Synergistic antitumor effects of transarterial viroembolization for multifocal hepatocellular carcinoma in rats. Hepatology. 2008; 48 1864-1873 2 Ebert O, Shinozaki K, Huang T G, Savontaus M J, Garcia-Sastre A, Woo S LC. Oncolytic vesicular stomatitis virus for treatment of orthotopic hepatocellular carcinoma in immune-competent rats. Cancer Research. 2003; 63 3605-3611 3 Ebert O, Shinozaki K, Kournioti C, Park M S, Garcia-Sastre A, Woo S LC. Syncytia induction enhances the oncolytic potential of vesicular stomatitis virus in virotherapy for cancer. Cancer Research. 2004; 64 3265-3270 4 Kirn , et al . Replication-selective virotherapy: biological principles, risk management and future directions. Nature Medicine. 2001; 7 781-787 5 Marozin S, Altomonte J, Stadler F, Thasler W E, Schmid R M, Ebert O. Inhibition of the IFN-beta response in hepatocellular carcinoma by alternative spliced isoform of IFN regulatory factor-3. Molecular Therapy. 2008; 16 1789-1797 6 Shinozaki K, Ebert O, Woo S LC. Eradication of advanced hepatocellular carcinoma in rats via repeated hepatic arterial infusions of recombinant VSV. Hepatology. 2005; 41 196-203 7 Stojdl. et al . VSV strains with defects in their ability to shutdown innate immunity are potent systemic anti-cancer agents. Cancer Cell. 2003; 4 263-275 Dr. med. Oliver Ebert II. Medizinische Klinik und Poliklinik, Klinikum rechts der Isar, Technische Universität München Ismaningerstr. 32 81675 München Telefon: 089/4140-2261 Fax: 089/4140-2258 eMail: oliver.ebert@lrz.tum.de