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Synfacts 2010(1): 0037-0037  
DOI: 10.1055/s-0029-1218416
Synthesis of Materials and Unnatural Products
© Georg Thieme Verlag Stuttgart ˙ New York

One Pot per Generation

Contributor(s): Timothy M. Swager, Brett VanVeller
X. Ma*, J. Tang, Y. Shen*, M. Fan, H. Tang, M. Radosz
Zhejiang University, Hangzhou, P. R. of China and University of Wyoming, Laramie, USA
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Publication History

Publication Date:
21 December 2009 (online)

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Significance

High-generation dendrimers were synthesized through application of kinetically selective ”click" reactions between monomers. The high yields and avoidance of tedious protection-deprotection steps allowed for a rapid one-pot-per-generation sequence.