Generation of Gold Nanoparticles via Direct Thiol-Capping with THP-Protected Thiols without Deprotection

Abstract

Alkanethiol-capped gold nanoparticles are prepared directly from the corresponding S-tetrahydropyranyl-protected thiols by treatment of HAuCl₄ in the presence of a reducing agent such as triethylsilane, NaBH₄, or superhydride.

Key words

gold nanoparticle - THP thioether - alkanethiol - triethylsilane - functional group

References and Notes

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8

No reaction of 1 was confirmed by the addition of TES.

9

See Supporting Information.

12

AuNP obtained by the reduction with NaBH₄ or LiBH₄ shows its weight loss to be ca. 25% (ref. 2b,c).

13

The particle size was similar to the case with unprotected dodecanethiol.

15

Attempted exchange with THP thioether with AuNP was found to be unsuccessful.