Synthesis of Functionalized N-Vinyl Nitrogen-Containing Heterocycles

Susana M. M. Lopes; Ana Matos Beja; Manuela Ramos Silva; José A. Paixão; Francisco Palacios; Teresa M. V. D. Pinho e Melo

doi:10.1055/s-0029-1216846

PAPER

Synthesis of Functionalized N-Vinyl Nitrogen-Containing Heterocycles

Susana M. M. Lopes^a, Ana Matos Beja^b, Manuela Ramos Silva^b, José A. Paixão^b, Francisco Palacios^c, Teresa M. V. D. Pinho e Melo*^a
^a Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal
Fax: +351(239)827703; e-Mail: tmelo@ci.uc.pt;
^b Department of Physics, University of Coimbra, 3004-516 Coimbra, Portugal
^c Department of Organic Chemistry I, Faculty of Pharmacy, University of the Basque Country, Apartado 450, 01080 Vitoria, Spain

Abstract

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Abstract

Microwave-assisted 1,3-dipolar cycloaddition of the azomethine ylide generated by ring opening of a N-vinylaziridine gave new N-vinyl derivatives of pyrrolidine, 3-pyrroline, octahydropyrrolo[3,4-c]pyrrole and 1,2,4-triazolidine.

Key words

microwave-assisted 1,3-dipolar cycloaddition - Michael addition - allenes - N-vinyl heterocycles - aziridines - pyrrolidines - 3-pyrrolines - octahydropyrrolo[3,4-c]pyrroles - 1,2,4-triazolidines

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Referenzen

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