A Novel and Convenient
Synthesis of ‘Reversed’ Diamidino 2,5-Aryl- and 2,5-Azaheterocycle-Substituted
Furans

Laixing Hu; David W. Boykin

doi:10.1055/s-0029-1216817

SHORTPAPER

A Novel and Convenient Synthesis of ‘Reversed’ Diamidino 2,5-Aryl- and 2,5-Azaheterocycle-Substituted Furans

Laixing Hu, David W. Boykin*
Department of Chemistry, Georgia State University, Atlanta, GA 30303, USA
Fax: +1(404)4135505; e-Mail: dboykin@gsu.edu;

Abstract

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Abstract

A novel and convenient two-step synthesis of ‘reversed’ diamidino 2,5-aryl- and 2,5-azaheterocycle-substituted furans is described. The key step, a Stille cross-coupling reaction between N-(bromoaryl)arenecarboxamidines and 2,5-bis(tri-n-butylstannyl)furan, is reported for the first time.

Key words

reversed amidines - thioimidates - Stille cross-coupling reaction - furans - N-heterocycles

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References

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