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Synlett 2009(7): 1123-1125  
DOI: 10.1055/s-0028-1088114
LETTER
© Georg Thieme Verlag Stuttgart ˙ New York

A Novel and Facile One-Pot Synthesis of 3-Aryl-4H-benzo[1,4]thiazin-2-amine

Majid M. Heravi*, Bita Baghernejad, Hossein A. Oskooie
Department of Chemistry, School of Sciences, Azzahra University, Vanak, Tehran 1993891176, Iran
Fax: +98(21)88047861; e-Mail: mmh1331@yahoo.com;
Further Information

Publication History

Received 1 December 2008
Publication Date:
26 March 2009 (online)

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Abstract

A high-yielding and fast method for the synthesis of 3-aryl-4H-benzo[1,4]thiazin-2-amine via one-pot, three-component reaction of an aromatic aldehyde, isocyanide, and o-amino thiophenol using PTSA as a catalyst is described.

Key words

one-pot synthesis - 3-aryl-4H-benzo[1,4]thiazin-2-amine - catalyst

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